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irinotecan loaded bolaamphiphilic nanovesicle

Based on

1 Patents
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

irinotecan hydrochloride

camptosar CPT-11
Type Single Compound
Formula C33H39ClN4O6
Role loaded material
3

bolaamphiphilic compound-lipid mixture

Type Complex Compound
Formula
Role layer

Applications

Area Application Nanomaterial Variant Source
drug delivery

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • {2-[(5-{[(9E)-7-hydroxy-17-({11-[(9E)-12-hydroxy-13-({5-oxo-5-[2-(trimethylazaniumyl)ethoxy]pentanoyl}oxy)octadec-9-enamido]undecyl}carbamoyl)heptadec-9-en-6-yl]oxy}-5-oxopentanoyl)oxy]ethyl}trimethylazanium dichloride
  • cholesteryl hemisuccinate
  1. dnjDcgS5sV
Product

irinotecan loaded bolaamphiphilic nanovesicle

Size: not specified

Medium: phosphate buffer solution

Support: none

References

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