Loading ...

poly(ethylene glycol) methyl ether/docetaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Based on

1 Patents
2014 Most recent source

Composition

1

acetylated carboxymethylcellulose

CMC-Ac
Type Biomolecule
Formula
Role raw materials
2

poly(ethylene glycol) methyl ether

mPEG-OH
Type Polymer
Formula
Role graft
3

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Dtx Doc
Type Single Compound
Formula C43H53NO14
Role loaded material

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

More information available to subscribers only.

Or, view sample content

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

More information available to subscribers only.

Or, view sample content

Biological effects

Biological system Test details Nanomaterial Variant Source
EMT-6 tumor-bearing female BALB/c mouse

More information/entries available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. 59sstpnLmel14TVRfSZMFqjQqs0pf
  2. 8nt8tcN0SFF4uSowE7JQyycC8VG28oRi0qy2M20Kxq6UJ7SWwk0wLp2xA0NaqUN5mf1agI
Product

poly(ethylene glycol) methyl ether/docetaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 117.8 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. Zcv5NMMEd6pmleZJswxPYzAz7nYzX
  2. 35sPf2KFjmWATkw3gsUpVJrBRFghBMOwEYN2BNsTA3YjaK3ijs2FFlG1Z5Gq7rO44z2UXB
Product

poly(ethylene glycol) methyl ether/docetaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 118.4 nm

Medium: water

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. 9vaOcs1SWzBeF9qJgJnEjXZJZ4XDR
  2. nnFqlwZGlud5PMisdlMOdUagTDz6z53a0QMaMISDCfYORrqOPl4fju1rO5MSAVqMOKa94c
Product

poly(ethylene glycol) methyl ether/docetaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 102.1 nm

Medium: water

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. KpMARu7EixJwbzI8CgqvVce8jLWcm
  2. zV7xyshtTFvYv9plLwfJR9PgDtlGq0WL3bzGJgaFOl7Jva3bcdsiHmJOLIcwdSKsENrsJ6
Product

poly(ethylene glycol) methyl ether/docetaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 116 nm

Medium: water

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. 3Ssa1Hf5eNGZCXhmbXN46BK08e4Mr
  2. QQiOhLgIoBMYi5kOa1kH5B5jv832Byz8PmS2EyXbinPFd6iHjMYDticqsoceagCw1ido8r
Product

poly(ethylene glycol) methyl ether/docetaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 107.2 nm

Medium: water

Support: none

References

Full content is available to subscribers only

To view content please choose from the following:


Sign up for a free trial