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PLA/PLA-PEG/PLA-PEG-lys(urea)glu/docetaxel nanoparticles

Based on

1 Patents
2014 Most recent source

Composition

1

PLA

Type Polymer
Formula
Role core
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role fillers
3

PLA-PEG

Type Polymer
Formula
Role layer
4

S,S-2-{3-[1-carboxy-5-amino-pentyl]-ureido}-pentanedioic acid-terminated poly(lactide-b-ethylene glycol)

PLA-PEG-lys(urea)glu
Type Polymer
Formula
Role layer

Biological effects

Biological system Test details Nanomaterial Variant Source
naïve non human primate

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • S,S-2-{3-[1-carboxy-5-amino-pentyl]-ureido}-pentanedioic acid-terminated poly(lactide-b-ethylene glycol)
  • PLA-PEG
  • PLA
See all (4)
  1. I2otHRhxksN2cbiEwRGYMLOl4WnCe0rExiW5ZxTq15ohmzym
  2. nWHoMk1bAgCJ8I
Product

PLA/PLA-PEG/PLA-PEG-lys(urea)glu/docetaxel nanoparticles

Size: not specified

Medium/Support: none

References

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