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poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Based on

1 Patents
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

acetylated carboxymethylcellulose

CMC-Ac
Type Biomolecule
Formula
Role raw materials
2

poly(ethylene glycol) methyl ether

mPEG-OH
Type Polymer
Formula
Role graft
3

cabazitaxel

CABA CTX CBZ
Type Single Compound
Formula C45H57NO14
Role loaded material

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cancer associated fibroblasts

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. SQTskImTNQe7vMs01RoK8Bg9SSXnB
  2. DvMMUrJvylATKWA1zPNj2BulqiN7MXKCDoQjDpaJPLwP4Cs4JvJMhALsevg32SCSengfG9
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 90.01 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. rUfgMgBTlzGCn3TSFzQ1TmMO1oMiN
  2. FNsSeMmjG9EVVExSbZfRb3ocO0fp3cqSAfKWCbfqRZzhamZdew29OKUA5QefV0XCY797Ai
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 62.98 nm

Medium: water

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. Y3li9XU0y5axnP4MpOHXAx6weVCwc
  2. rFnb1OjSzn6OnaM9jSM0U2AWpJhfEbyq5dk77wQ7fMLFUTHg1UNdfCaPRKPaIJmHOUewm8
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 38.88 nm

Medium: water

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. U89wZxQRhbo11BB9f9n5Aibl7fiB3
  2. GbJi68pwrghr5c168Koo4qnRliRzNwF71HXCmyBDwn88lU2MeeLyHC7WKpLrj2CTOGmdZ4
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 33.38 nm

Medium: water

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. KEmyirFzUU45ZF9jt1fnRk3UiXjJi
  2. yxer1MWwahGFdc4VWh3PnMgFJkJyL5nBfyKf7trCJQRSQTznkL0Uhj0ruqrMCvonPO6YOn
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 79.1 nm

Medium: water

Support: none

References

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