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poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Based on

1 Patents
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

acetylated carboxymethylcellulose

CMC-Ac
Type Biomolecule
Formula
Role raw materials
2

poly(ethylene glycol) methyl ether

mPEG-OH
Type Polymer
Formula
Role graft
3

cabazitaxel

CABA CBZ CTX
Type Single Compound
Formula C45H57NO14
Role loaded material

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cancer associated fibroblasts

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. d5gE7AapGWabjnwNyawoEw3BTUdyR
  2. Vl5WHjT2HQiyaCExd3OyswWtULMybL7x1OmHSkRJycEmJ9lFYhGVCQkMXxBw5Hh4yR22wk
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 76.92 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. pDAALS2DqJciDRHSZgcTQ13ZX8aiz
  2. cNsrnM0BIIlC9uKhYSqmO4oRglgCfTafEvs69sFyrjADPdqq5yOg3aUAcMDDFWduD35exg
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 45.96 nm

Medium: water

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. 1EvDIIjLueirf4Ed35xZDwtJJP8KP
  2. pmNKpFfUiMCGu8OCMz1Xv2efFnE869sHy6bd585H84vqkI1crhUPylWv7nfsAxfkPfncp9
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 55.22 nm

Medium: water

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. 2tXL6vXptTV2T8Nnxzz3NKDLfdwhS
  2. ZWjTLqX5qzXnETgzRuQAysH7xq4SxaeKpSQEK2kBQ5vli9tYIl06GQoXHptC48WNymVcqu
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 90.01 nm

Medium: water

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. PfnXn7l648Nz6RpiU82E4gGftv8Y9
  2. VIHaji1nGCe5PCSQRLplq4R0w28K5uyl4ls1RSj9ZI8Nw259vNKjB53Hr1XtdYV4UKk2n9
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 47.82 nm

Medium: water

Support: none

References

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