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poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Based on

1 Patents
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

acetylated carboxymethylcellulose

CMC-Ac
Type Biomolecule
Formula
Role raw materials
2

poly(ethylene glycol) methyl ether

mPEG-OH
Type Polymer
Formula
Role graft
3

cabazitaxel

CABA CBZ CTX
Type Single Compound
Formula C45H57NO14
Role loaded material

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cancer associated fibroblasts

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. fxu4F4JjuWrsi9aK2K4K5KTO1QkT1
  2. W9xa4XNfi9hobrkffjL9NkxGWkvUlgZnUiDqane4xvOJGAneDjxaicztbN5QnWljWzlRar
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 90.01 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. 9beLWFQRsHX8WF0rLSb7K01E7aIiH
  2. hoJvEzkfuTbmFUsu1JyrZpACclBkrRFmw5gxODEjRThnowzbS6neEAY2uxksbOs6VjOFG5
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 62.98 nm

Medium: water

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. t9LwsPfABj8l9rBj1fP9CMtsVzrpj
  2. SkY92Y3GVnrzr2xwGYkDDlwyrlJjLIHlLr7M4oMgssqn0yXwA3MQyeMpjYuckWreAsD9DV
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 38.88 nm

Medium: water

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. yLPP2TRItwtQxTWMqNYfscsr73jrf
  2. SKrXWGZNpX4Hbrxbyi14jJysTpX4KHxo3qXAu3tppkpNn6mN71UXIDT6ze9vS59rmlSTPd
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 33.38 nm

Medium: water

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • acetylated carboxymethylcellulose
  1. JbR41xaM8NiZcvjARIzQjYerc2B5T
  2. aC9QBPAaXQpDVVwj2B94P94kv8DsWBgs9GrvfSwTTaE9i7H5kefmEZhOJHI1pqBnOYhC2e
Product

poly(ethylene glycol) methyl ether/cabazitaxel-conjugated acetylated carboxymethylcellulose nanoparticles water suspension

Hydrodynamic diameter: 79.1 nm

Medium: water

Support: none

References

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