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methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Based on

5 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic acid)-methacrylic acid copolymer

PLA-MAA copolymer
Type Complex Compound
Formula
Role carriers
2

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
A-549 human lung adenocarcinoma cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • succinic acid anhydride
  • H40
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • succinic acid anhydride
  • H40
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • succinic acid anhydride
  • H40
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol)-branched poly(ethylene imine)-poly(ε-caprolactone)
  • methotrexate
  1. EJhw04DDsEDr2Nk9y0bxm
  2. xf6m4
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
  1. hNkh
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Size: not specified

Medium: phosphate buffer solution

Support: none

References

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