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methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic acid)-methacrylic acid copolymer

PLA-MAA copolymer
Type Complex Compound
Formula
Role carriers
2

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role loaded material

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(methacrylic acid-co-methyl methacrylate) 1:2
  • poly(lactic acid)
  • methotrexate
  1. 5qjiTOaxpSV6e
  2. 1JH6AerV07kxyY8kedG72XGM9uuIvtSxFlZOcWOtFZcNvDsX
  3. rJcPxebmBXt1QI
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Hydrodynamic diameter: ~ 242.1 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(methacrylic acid-co-methyl methacrylate) 1:2
  • poly(lactic acid)
  • methotrexate
  1. NXE4nbVwSZkul
  2. BLE8rNZJGfkkr1BSzNeJKewGiWXMHBlGwq9CJMVfZ9vJ76aa
  3. egRMsnjQCnXRNr
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Hydrodynamic diameter: ~ 308.4 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(methacrylic acid-co-methyl methacrylate) 1:2
  • poly(lactic acid)
  • methotrexate
  1. hoj2iYt8B4KpV
  2. Qy1jQpdk6rjiwKSba1lLUHlUAyMEjOdvAcRJPyS01JfETVHq
  3. NlwXQPKEJeTXru
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Hydrodynamic diameter: ~ 241.1 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(methacrylic acid-co-methyl methacrylate) 1:2
  • poly(lactic acid)
  • methotrexate
  1. zFFfGSEJRnCcJ
  2. sDq0owLlhGlc4DZPVUz3XPrBHX59jjjMw94olLfvZz7PASre
  3. BnzsFlorLEq61j
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Hydrodynamic diameter: ~ 222.1 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(methacrylic acid-co-methyl methacrylate) 1:2
  • poly(lactic acid)
  • methotrexate
  1. czegIDrf5ymCS
  2. WbLnTAF02NvhN2YuAVWiPVGSJZp3Zqs30KeZkNt3lHLz2lyi
  3. 17iURlgRQ7qjP4
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Hydrodynamic diameter: ~ 227.3 nm

Medium: water

Support: none

References

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