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methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic acid)-methacrylic acid copolymer

PLA-MAA copolymer
Type Complex Compound
Formula
Role carriers
2

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role loaded material

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(methacrylic acid-co-methyl methacrylate) 1:2
  • poly(lactic acid)
  • methotrexate
  1. iELmLd3yxYxMA
  2. 0s0opzq9OtuwOT71jhySkwKWNtBwUPZMijdGU9kM8b0XUrFS
  3. zef7c02wHCJdle
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Hydrodynamic diameter: ~ 242.1 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(methacrylic acid-co-methyl methacrylate) 1:2
  • poly(lactic acid)
  • methotrexate
  1. 2LSH2ZF6GNKyY
  2. A6lfEIGHKZQzFKgQ0jtvAxrJDb3QHc4Jxu2GoRKqpfqIYoaF
  3. Qp2YyjLpfypxvw
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Hydrodynamic diameter: ~ 308.4 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(methacrylic acid-co-methyl methacrylate) 1:2
  • poly(lactic acid)
  • methotrexate
  1. HHGvdbx8S2mWo
  2. 37XdQys1GWKzqyTa2smgozOmCugwpDyPJl51Bwqv9xAWxSlE
  3. ZZuXe5ShcffZk0
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Hydrodynamic diameter: ~ 241.1 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(methacrylic acid-co-methyl methacrylate) 1:2
  • poly(lactic acid)
  • methotrexate
  1. ACXpUGKGXPZed
  2. 2uxDautmmVNqLwzrCPR6y5fz52KCpZcf5P4Gp2zBKf3pZnd7
  3. XeGb7miGEubHqC
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Hydrodynamic diameter: ~ 222.1 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(methacrylic acid-co-methyl methacrylate) 1:2
  • poly(lactic acid)
  • methotrexate
  1. dM6DkmBFSjs88
  2. ebJ8j2q6aR52bQjfMXRpTa2FohAqGUheBl93DWfh2P2ca1fD
  3. s0AbkdE8L9LGS2
Product

methotrexate-loaded poly(lactic acid)-methacrylic acid copolymeric nanoparticles

Hydrodynamic diameter: ~ 227.3 nm

Medium: water

Support: none

References

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