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praziquantel-loaded tripalmitin solid lipid nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

hexadecanoic acid [2-(1-oxohexadecoxy)-1-(1-oxohexadecoxymethyl)ethyl] ester

2,3-di(hexadecanoyloxy)propyl hexadecanoate triacyl glyceryl palmitate glyceryl tripalmitate glycerol tripalmitate tripalmitin glyceride triglyceride Dynasan® 116 tripalmitin T8127 Dyna TG TP
Type Single Compound
Formula C51H98O6
Role carriers
2

praziquantel

PZQ
Type Single Compound
Formula C19H24N2O2
Role loaded material
3

lecithin

Type Complex Compound
Formula
Role layer
4

polyoxyethylene-polyoxypropylene polymer

PEO-PPO-PEO tri-block copolymer P188 Lutrol F68 Poloxamer 188 P188
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on solvents

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
Charle Foster strain albino rats

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Preparation

Method 1

Type: Physical formation
Source:
  1. obU
  2. 0p1U9x
  3. tB8
Product

praziquantel-loaded tripalmitin solid lipid nanoparticles

Hydrodynamic size: 165.58 - 172.82 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • hexadecanoic acid [2-(1-oxohexadecoxy)-1-(1-oxohexadecoxymethyl)ethyl] ester
  • lecithin
  • praziquantel
  1. AxOqmQX
Product

praziquantel-loaded tripalmitin solid lipid nanoparticles

Hydrodynamic size: 229.97 - 252.83 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • hexadecanoic acid [2-(1-oxohexadecoxy)-1-(1-oxohexadecoxymethyl)ethyl] ester
  • lecithin
  • praziquantel
  1. pJQoLpR
Product

praziquantel-loaded tripalmitin solid lipid nanoparticles

Hydrodynamic size: 97.62 - 99.58 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • hexadecanoic acid [2-(1-oxohexadecoxy)-1-(1-oxohexadecoxymethyl)ethyl] ester
  • lecithin
  • praziquantel
  1. 7g3ZJuI
Product

praziquantel-loaded tripalmitin solid lipid nanoparticles

Hydrodynamic size: 250.1 - 309.5 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • hexadecanoic acid [2-(1-oxohexadecoxy)-1-(1-oxohexadecoxymethyl)ethyl] ester
  • lecithin
  • praziquantel
  1. RuTa49p
Product

praziquantel-loaded tripalmitin solid lipid nanoparticles

Hydrodynamic size: 120.02 - 123.18 nm

Medium: water

Support: none

References

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