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glibenclamide-loaded poly(D,L-lactic-co-glycolic acid) nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role raw materials
2

Glibenclamide

glibenclamide GLM GB
Type Single Compound
Formula C23H28ClN3O5S
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Wistar albino rat

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • Glibenclamide
  1. yMjGzy7CHQ5s61uv3dJz8unIk7uafnMsLYs7
  2. PwZp8z9g0XY76C5YkbEV3n
Product

glibenclamide-loaded poly(D,L-lactic-co-glycolic acid) nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • Glibenclamide
  1. i4PYCXxzGyE58iWG00S4Zl5JycP0aBzs0uBm
  2. p9GmrTy9rnACHObCH02sig
Product

glibenclamide-loaded poly(D,L-lactic-co-glycolic acid) nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

glibenclamide-loaded poly(D,L-lactic-co-glycolic acid) nanoparticles

Hydrodynamic diameter: 556.72 - 567.28 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • Glibenclamide
  1. aLHUQDlj8raC1vcZcZYCBLaZobz7hpKR1WJe
  2. E9ud7jhKz9QfYZxzimhKEx
Product

glibenclamide-loaded poly(D,L-lactic-co-glycolic acid) nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • Glibenclamide
  1. lWSUnN2kjNTkztUpIEgrTCXBroaorYmNCrxs
  2. 45ClFGXcMuunrtSw6Gur3W
Product

glibenclamide-loaded poly(D,L-lactic-co-glycolic acid) nanoparticles

Size: not specified

Medium/Support: none

References

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