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cyclosporine A loaded PLGA/Eudragit RL100 nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

cyclosporine A

CyA
Type Single Compound
Formula C62H111N11O12
Role core
2

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role layer
3

Eudragit RL100

Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug permeation in franz diffusion cell

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • Eudragit RL100
  • poly(lactic-co-glycolic acid)
  • water
See all (4)
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Product

cyclosporine A loaded PLGA/Eudragit RL100 nanoparticles

Hydrodynamic size: 215.7 - 254.7 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

cyclosporine A loaded PLGA/Eudragit RL100 nanoparticles

Size: not specified

Medium: simulated lacrimal fluid

Support: none

Method 3

Type: Physical formation
Source:
Product

cyclosporine A loaded PLGA/Eudragit RL100 nanoparticles

Hydrodynamic size: 208.3 - 244.3 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Product

cyclosporine A loaded PLGA/Eudragit RL100 nanoparticles

Hydrodynamic size: 156.0 - 185.0 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Product

cyclosporine A loaded PLGA/Eudragit RL100 nanoparticles

Hydrodynamic size: 151.2 - 171.2 nm

Medium: water

Support: none

References

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