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crizotinib-loaded PEGylated cholesterol/hydrogenated soy phosphatidylcholine liposomes

Based on

1 Patents
2013 Most recent source

Composition

1

ammonium sulfate solution

Type Complex Compound
Formula
Role core
2

crizotinib sulfate

Type Complex Compound
Formula
Role loaded material
3

hydrogenated soy phosphatidylcholine

Type Complex Compound
Formula
Role layer
4

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
5

DSPE-PEG-GSH

Type Polymer
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug leakage

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Biological effects

Biological system Test details Nanomaterial Variant Source
BCRP knock-out mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • crizotinib
  1. U70ARPIAMBeaCAZKJSGdgJAw3XP7vfmfBRamkWyrH6D4DFKPdMvvC3VkU
Product

crizotinib-loaded PEGylated cholesterol/hydrogenated soy phosphatidylcholine liposomes

Size: ~ 100 nm

Medium/Support: none

References

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