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oxaliplatin-loaded hyaluronic acid-coupled chitosan tripolyphosphate nanoparticles

Based on

1 Articles
2010 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

chitosan

Type Biomolecule
Formula
Role carriers
2

tripolyphosphate anion

tripolyphosphate TPP anion TPP
Type Single Compound
Formula P3O105-
Role fillers
3

hyaluronic acid

HA
Type Biomolecule
Formula
Role graft
4

[oxalato(l-trans-1,2-diaminocyclohexane)]platinum(II)

oxaliplatin eloxatin elplat L-OHP OXA Oxa OX
Type Single Compound
Formula C8H14N2O4Pt
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
in-vitro oxaliplatin release from nanoparticle-encapsulating enterically protected pellet

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57BL mouse with human colon cancer HT-29 cells (colon mucosa)

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
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  2. seRULBQJC9TnvMpktduFVfVawkVKCzN7neOpQROeO4w9kpRpzfdgGzscM1Wddf
  3. TxfSjO3NhfrhGN
  4. ZlVAW0I4SMdRCL
Product

oxaliplatin-loaded hyaluronic acid-coupled chitosan tripolyphosphate nanoparticles

Diameter: 152 nm

Medium/Support: none

References

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