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gemcitabine/Fe3O4 albumin nanospheres

Based on

1 Articles
2013 Most recent source

Composition

1

bovine serum albumin

Fraction V BSA
Type Biomolecule
Formula
Role raw materials
2

glutaraldehyde

Type Single Compound
Formula C5H8O2
Role framework element
3

Fe3O4 magnetic nanoparticles

Type Nano Material
Formula
Role loaded material
4

(4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl]-1,2-dihydropyrimidin-2-one)

2',2'-difluoro-2'-deoxycytidine 2'-deoxy-2',2'-difluorocytidine 2',2'-difluorodeoxycytidine gemcitabine gemzar dFdC GEM Gem gem
Type Single Compound
Formula C9H11F2N3O4
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
L929 fibroblasts

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Preparation

Method 1

Type: Physical formation
Source:
  1. KOCxLFMEpDeWDUn
Product

gemcitabine/Fe3O4 albumin nanospheres

Diameter: 131 - 317 nm

Medium: ethanol

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • Fe3O4 magnetic nanoparticles
  • (4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl]-1,2-dihydropyrimidin-2-one)
  • bovine serum albumin
  1. M9p22Y
Product

gemcitabine/Fe3O4 albumin nanospheres

Diameter: ~ 185 nm

Medium/Support: none

References

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