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docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Based on

1 Articles
2013 Most recent source

Composition

1

5.0 G polypropylenimine dendrimer-polyethylene glycol 7500-folate nanoconjugate

folate-PEG7500-5.0 G PPI nanoconjugate PPI-PEG7500-Folate PPIP7.5FA
Type Nano Material
Formula
Role carriers
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
in vitro drug release profile of DTX dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Biological effects

Biological system Test details Nanomaterial Variant Source
estrogen receptor-positive human breast cancer MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. CzSodQBTIWsLZaHu0qrssN7j15V1Ph21S2qcRvydMBAQorh
Product

docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. LkkPDU3n2oqUzmAkdzub3s0sb5YO3pOrSUSwJHCI8hZWLvK
Product

docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  1. tlhSfR89XzszGNZLVzlxDbHFWPat4SAWPJbOvF5mA7qwZsB
Product

docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  1. r1QeV9UOtCjQ9shVSvdk6jVNMffjhCFKF1g58hfkImikSzO
Product

docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  1. Gyz5hPFsC3efsQDGQnkqH66F5DM2wcqPi9NwDCz7cM8JqYB
Product

docetaxel-loaded 5.0 G polypropylenimine dendrimer-polyethylene glycol 1000-folate nanoconjugate

Size: not specified

Medium/Support: none

References

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