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paclitaxel-loaded soy phosphatidylcholine/glycerol dioleate/polysorbate 80-based liquid crystalline nanoparticles

Based on

3 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Pt-containing 4-armed polymer nanoparticles

Pt-PAZMB-b-POEGMA nanoparticles
Type Nano Material
Formula
Role carriers
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PCL PAC PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
MDA-MB-231 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • Pt-PAZMB-b-POEGMA
  • Paclitaxel
  1. GCt
Product

paclitaxel-loaded soy phosphatidylcholine/glycerol dioleate/polysorbate 80-based liquid crystalline nanoparticles

Hydrodynamic diameter: 585.6 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • Pt-PAZMB-b-POEGMA
  • Paclitaxel
  1. Md7FtPSBWy6e4jlV36
Product

paclitaxel-loaded soy phosphatidylcholine/glycerol dioleate/polysorbate 80-based liquid crystalline nanoparticles

Hydrodynamic diameter: 65.7 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • soy phosphatidylcholine
  • polyoxyethylene (20) sorbitan monooleate
  • Paclitaxel
See all (4)
  1. jrLMAS9byzO3Dd78Aoftm
  2. Uk9jYbC5
Product

paclitaxel-loaded soy phosphatidylcholine/glycerol dioleate/polysorbate 80-based liquid crystalline nanoparticles

Hydrodynamic diameter: 74.18 - 95.22 nm

Medium: HEPES buffer

Support: none

References

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