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paclitaxel-loaded 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy(polyethylene-glycol)-2000/cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine liposomes

Based on

1 Articles
2017 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy(polyethylene-glycol)-2000/cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine

DPPC/DSPE-PEG-2000/cholesterol/DOPC
Type Complex Compound
Formula
Role layer
3

Paclitaxel

Plaxicel Abraxane Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse xenografted with human breast cancer MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
  • 1,2-dioleoyl-sn-glycero-3-phosphocholine
  • cholesterol
See all (5)
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  2. ZC6ySJbXs2P4p
Product

paclitaxel-loaded 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy(polyethylene-glycol)-2000/cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine liposomes

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

paclitaxel-loaded 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy(polyethylene-glycol)-2000/cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine liposomes

Diameter: 101.22 - 110.06 nm

Medium: phosphate buffer solution

Support: none

References

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