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paclitaxel-loaded 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy(polyethylene-glycol)-2000/cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine liposomes

Based on

1 Articles
2017 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy(polyethylene-glycol)-2000/cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine

DPPC/DSPE-PEG-2000/cholesterol/DOPC
Type Complex Compound
Formula
Role layer
3

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Source
paclitaxel release dependent on laser irradiation presence

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Applications

Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
BALB/c mouse xenografted with human breast cancer MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
  • 1,2-dioleoyl-sn-glycero-3-phosphocholine
  • cholesterol
See all (5)
  1. 3Yd62ZGDV39dMyJ2Rg6
  2. dhhQEZg3lS8No
Product

paclitaxel-loaded 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy(polyethylene-glycol)-2000/cholesterol/1,2-dioleoyl-sn-glycero-3-phosphocholine liposomes

References

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