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siBRD4-loaded methoxy-terminated poly(ethylene glycol)-block-poly(2-(hexamethyleneimino)ethyl methacrylate) nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

methoxy-terminated poly(ethylene glycol)-block-poly(2-(hexamethyleneimino)ethyl methacrylate) nanoparticles

MeO-PEG-b-PHMEMA NP
Type Nano Material
Formula
Role carriers
2

tumor-targeting and cell-penetrating peptide-amphiphile

TCPA
Type Biomolecule
Formula
Role loaded material
3

small interfering RNA against bromodomain 4

siBRD4
Type Biomolecule
Formula
Role loaded material

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
AR positive LNCaP prostate cancer cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • small interfering RNA against bromodomain 4
  • methoxy-terminated poly(ethylene glycol)-block-poly(2-(hexamethyleneimino)ethyl methacrylate)
  • tumor-targeting and cell-penetrating peptide-amphiphile
  1. WWu7XBfek0LkwNtNsfkUaeTsjM2G8YTdfXrcM5YK
Product

siBRD4-loaded methoxy-terminated poly(ethylene glycol)-block-poly(2-(hexamethyleneimino)ethyl methacrylate) nanoparticles

Size: not specified

Medium/Support: none

References

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