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DY677-labeled siLuc loaded methoxy-terminated poly(ethylene glycol)-block-poly(2-(hexamethyleneimino)ethyl methacrylate) nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

methoxy-terminated poly(ethylene glycol)-block-poly(2-(hexamethyleneimino)ethyl methacrylate) nanoparticles

MeO-PEG-b-PHMEMA NP
Type Nano Material
Formula
Role carriers
2

tumor-targeting and cell-penetrating peptide-amphiphile

TCPA
Type Biomolecule
Formula
Role loaded material
3

DY677-labeled small interfering RNA against luciferase

DY677-labeled siLuc
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
pH stability

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Applications

Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
luciferase-expressing HeLa (Luc-HeLa) cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • methoxy-terminated poly(ethylene glycol)-block-poly(2-(hexamethyleneimino)ethyl methacrylate)
  • tumor-targeting and cell-penetrating peptide-amphiphile
  • DY677-labeled small interfering RNA against luciferase
  1. yOBezC6jlve1edJ5pNEBvbMnfQ9GTdePowdIU2Yp
Product

DY677-labeled siLuc loaded methoxy-terminated poly(ethylene glycol)-block-poly(2-(hexamethyleneimino)ethyl methacrylate) nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • methoxy-terminated poly(ethylene glycol)-block-poly(2-(hexamethyleneimino)ethyl methacrylate)
  • tumor-targeting and cell-penetrating peptide-amphiphile
  • DY677-labeled small interfering RNA against luciferase
  1. J7aoHOOFjX2mZkLJhFQgPe2ZV4PNZg2mpMaMC8QL
Product

DY677-labeled siLuc loaded methoxy-terminated poly(ethylene glycol)-block-poly(2-(hexamethyleneimino)ethyl methacrylate) nanoparticles

References

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