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DACHPt-modified Panitumumab nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Panitumumab

Pan
Type Biomolecule
Formula
Role carriers
2

hydroxy(1,2-diaminocyclohexane)Pt(II) moiety

DACHPt moiety
Type Single Compound
Formula -C6H13N2OPt
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female BALB/cAnN.Cg-Foxnlnu/CrlNarl mouse xenografted with human colon adenocarcinoma HT29 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • dichloro(1,2-diaminocyclohexane)platinum(II)
  • water
  1. OQc3eAmIknHf4Acu
Product

DACHPt-modified Panitumumab nanoparticles

Hydrodynamic diameter: 133.85 - 150.15 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • dichloro(1,2-diaminocyclohexane)platinum(II)
  • water
  1. eqoLANWJXxZTDO8R
Product

DACHPt-modified Panitumumab nanoparticles

Hydrodynamic diameter: 153.80 - 157.00 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • dichloro(1,2-diaminocyclohexane)platinum(II)
  • water
  1. wUH9FaJGiqtwqSde
Product

DACHPt-modified Panitumumab nanoparticles

Hydrodynamic diameter: 120.28 - 124.52 nm

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • dichloro(1,2-diaminocyclohexane)platinum(II)
  • water
  1. joV6vPuHJnlz9tSX
Product

DACHPt-modified Panitumumab nanoparticles

Hydrodynamic diameter: 117.64 - 124.16 nm

Medium/Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • dichloro(1,2-diaminocyclohexane)platinum(II)
  • water
  1. hy18R0SuSZFCjMUI
Product

DACHPt-modified Panitumumab nanoparticles

Diameter: ~ 100 nm

Hydrodynamic diameter: 117.61 - 125.39 nm

Medium/Support: none

References

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