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PEG-modified gold-coated Gd(III)-loaded SCN-DOTA-doped silica-coated gold nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

gold

Type Single Compound
Formula Au
Role core
2

3-aminopropyl group-containing silica

Type Complex Compound
Formula
Role layer
3

p-benzyl isothiocyanate-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid tetrahydrochloride

2-[(4-isothiocyanatophenyl)methyl]-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid 2-(p-Isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid S-2(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid 2-(4-isothiocyanatobenzyl) 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid 2-(p-Isothiocyanatobenzyl)-DOTA p-SCN-Bn-DOTA p-SCN-Bz-DOTA SCN-DOTA
Type Single Compound
Formula C24H33N5O8S
Role loaded material
4

gadolinium(III) cation

gadolinium(III) ion gadolinium cation cationic Gd ion gadolinium(III) gadolinium ion gadolinium(3+) Gd(III) ion Gd(3+) ion Gd3+ ion Gd ion Gd(3+) Gd3+
Type Single Compound
Formula Gd3+
Role loaded material
5

gold

Type Single Compound
Formula Au
Role layer
6

methoxy-poly(ethylene glycol)-thiol

mPEG-SH
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
longitudinal magnetic resonance relaxivity

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. EnMvpdvcFKrAV1
Product

PEG-modified gold-coated Gd(III)-loaded SCN-DOTA-doped silica-coated gold nanoparticles

Diameter: 46 - 54 nm

Thickness: 11 - 15 nm

Thickness: 13 - 17 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  1. OL8EOFLi9OOWKYlQ1Lz
  2. qwqaDtBfvuBv
  3. lW2WmH2kurEcVg
Product

PEG-modified gold-coated Gd(III)-loaded SCN-DOTA-doped silica-coated gold nanoparticles

Diameter: 46 - 54 nm

Thickness: 11 - 15 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  1. hCbDHBkmrAtqr8otpyz
  2. X5HOTYtigXGZ
  3. XkIuEyL0Q8TSe0
Product

PEG-modified gold-coated Gd(III)-loaded SCN-DOTA-doped silica-coated gold nanoparticles

Diameter: 46 - 54 nm

Thickness: 11 - 15 nm

Thickness: 16 - 20 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  1. NaRTCiLZMDDleY
Product

PEG-modified gold-coated Gd(III)-loaded SCN-DOTA-doped silica-coated gold nanoparticles

Diameter: 46 - 54 nm

Thickness: 11 - 15 nm

Thickness: 13 - 17 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  1. vnB6FtKL8NysLV
Product

PEG-modified gold-coated Gd(III)-loaded SCN-DOTA-doped silica-coated gold nanoparticles

Diameter: 46 - 54 nm

Thickness: 11 - 15 nm

Thickness: 13 - 17 nm

Medium/Support: none

References

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