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siRNA-loaded folate-decorated polyethyleneimine-graft-polycaprolactone-block-poly(ethylene glycol) nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

folate-decorated polyethyleneimine-graft-polycaprolactone-block-poly(ethylene glycol)

FA-conjugated PEI-g-PCL-b-PEG PEI-g-PCL-b-PEG-Fol
Type Polymer
Formula
Role raw materials
2

siRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
human ovarian cancer SKOV-3 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • folate-decorated polyethyleneimine-graft-polycaprolactone-block-poly(ethylene glycol)
  1. Wg9YvCBHg968wj
Product

siRNA-loaded folate-decorated polyethyleneimine-graft-polycaprolactone-block-poly(ethylene glycol) nanoparticles

Size: 130 - 174 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

siRNA-loaded folate-decorated polyethyleneimine-graft-polycaprolactone-block-poly(ethylene glycol) nanoparticles

Hydrodynamic diameter: ~ 218 nm

Medium: phosphate buffer solution

Support: none

References

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