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docetaxel-loaded tocopheryl succinate-PEG-conjugated tLyP-1 peptide/D-α-tocopheryl succinate-conjugated hyaluronic acid nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

D-α-tocopheryl succinate-conjugated hyaluronic acid

Type Biomolecule
Formula
Role carriers
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material
3

tocopheryl succinate-PEG-conjugated tLyP-1 peptide

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
4T-1 murine breast cancer cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

docetaxel-loaded tocopheryl succinate-PEG-conjugated tLyP-1 peptide/D-α-tocopheryl succinate-conjugated hyaluronic acid nanoparticles

Hydrodynamic diameter: 106.9 - 113.1 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • D-α-tocopheryl succinate-conjugated hyaluronic acid
  • tocopheryl succinate-PEG-conjugated tLyP-1 peptide
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Product

docetaxel-loaded tocopheryl succinate-PEG-conjugated tLyP-1 peptide/D-α-tocopheryl succinate-conjugated hyaluronic acid nanoparticles

Size: not specified

Medium/Support: none

References

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