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lopinavir solid drug nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

poly(vinyl alcohol)

polyvinyl alcohol PVOH PVAI PVA
Type Polymer
Formula
Role raw materials
2

[1S-[1R*,(R*),3R*,4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenyl-methyl)pentyl]tetrahydro-a-(1-methyl-ethyl)-2-oxo-1-(2H)-pyrimidineacetamide

lopinavir LPV
Type Single Compound
Formula C37H48N4O5
Role raw materials
3

D-α-tocopheryl polyethylene glycol 1000 succinate

TPGS
Type Polymer
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol 1000 succinate
  • poly(vinyl alcohol)
  • [1S-[1R*,(R*),3R*,4R*]]-N-[4-[[(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenyl-methyl)pentyl]tetrahydro-a-(1-methyl-ethyl)-2-oxo-1-(2H)-pyrimidineacetamide
  1. EDJ84iuTzhpeHZsaXRGYY4KnFC
  2. l9RslGyYCg8ezGrN
  3. gCvLeOPk1mzISTL40eYdYuvOgHVV
  4. r3wAWBX
Product

lopinavir solid drug nanoparticles

Hydrodynamic diameter: ~ 110 - ~ 1000 nm

Medium: water

Support: none

References

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