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RGD peptide/ACPP-grafted chitosan-decorated Au@Se core-shell nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

gold nanorods

Au NR
Type Nano Material
Formula
Role core
2

selenium

Type Single Compound
Formula Se
Role layer
3

chitosan

Type Biomolecule
Formula
Role layer
4

(2S)-2-{2-[(2S)-2-amino-5-carbamimidamidopentanamido]acetamido}butanedioic acid

arginine-glycine-aspartate ligand Arginine-Glycine-Aspartic acid arginylglycylaspartic acid Arg-Gly-Asp peptide Arg-Gly-Asp RGD peptide RGD
Type Single Compound
Formula C12H22N6O6
Role graft
5

3-maleimidopropionyl moiety

Type Single Compound
Formula -C7H7NO3-
Role graft
6

activatable cell-penetrating peptide

ACPP
Type Biomolecule
Formula
Role graft

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human melanoma A375 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

RGD peptide/ACPP-grafted chitosan-decorated Au@Se core-shell nanoparticles

Hydrodynamic diameter: ~ 109 nm

Size: ~ 120 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
See all (4)
  1. MP3FbGrdH9Zhdk
Product

RGD peptide/ACPP-grafted chitosan-decorated Au@Se core-shell nanoparticles

Size: ~ 120 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

RGD peptide/ACPP-grafted chitosan-decorated Au@Se core-shell nanoparticles

Hydrodynamic diameter: ~ 118 nm

Size: ~ 120 nm

Medium: serum

Support: none

Method 4

Type: Physical formation
Source:
Product

RGD peptide/ACPP-grafted chitosan-decorated Au@Se core-shell nanoparticles

Hydrodynamic diameter: ~ 112 nm

Size: ~ 120 nm

Medium: 10 % FBS in DMEM

Support: none

References

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