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Paclitaxel-loaded glutamate-modified polyoxyethylene stearate-decorated poly(lactic-co-glycolic acid) nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
3

glutamate-modified polyoxyethylene stearate

Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
female Balb/C mice bearing mouse mammary (4T1) tumor

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • glutamate-modified polyoxyethylene stearate
  • poly(lactic-co-glycolic acid)
  • Paclitaxel
  1. Hb0jL0tUuHGdsBd06g4fH2H1M7mXMqyeN2w7Z
Product

Paclitaxel-loaded glutamate-modified polyoxyethylene stearate-decorated poly(lactic-co-glycolic acid) nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • glutamate-modified polyoxyethylene stearate
  • poly(lactic-co-glycolic acid)
  • Paclitaxel
  1. N3Pxg0SK6UzfrxOoX7gGFxviuOZrBgbxJfALA
Product

Paclitaxel-loaded glutamate-modified polyoxyethylene stearate-decorated poly(lactic-co-glycolic acid) nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • glutamate-modified polyoxyethylene stearate
  • poly(lactic-co-glycolic acid)
  • Paclitaxel
  1. n2Ia3kuuqO3CQ6QvAZATq9C8weiz1zrh5Qeyj
Product

Paclitaxel-loaded glutamate-modified polyoxyethylene stearate-decorated poly(lactic-co-glycolic acid) nanoparticles

Method 4

Type: Physical formation
Source:
Starting materials
  • glutamate-modified polyoxyethylene stearate
  • poly(lactic-co-glycolic acid)
  • Paclitaxel
  1. mKnPgdU78J3SjonGhfVR1Ee9dyHROEVnQpkaG
Product

Paclitaxel-loaded glutamate-modified polyoxyethylene stearate-decorated poly(lactic-co-glycolic acid) nanoparticles

Method 5

Type: Physical formation
Source:
Starting materials
  • glutamate-modified polyoxyethylene stearate
  • poly(lactic-co-glycolic acid)
  • Paclitaxel
  1. 2thUcLfkqpzL7zJFTz1YlRH2YQn313nadKDhe
Product

Paclitaxel-loaded glutamate-modified polyoxyethylene stearate-decorated poly(lactic-co-glycolic acid) nanoparticles

References

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