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lonidamine-encapsulating PEGylated peptide nanoparticles

Based on

2 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

peptide/protein

Type Biomolecule
Formula
Role carriers
2

lonidamine

LND
Type Single Compound
Formula C15H10Cl2N2O2
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c nude mouse bearing MCF-7R tumors

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • PEGylated heptapeptide-modified dendrimeric doxorubicin derivative
  • lonidamine
  1. 55Gzi6glBewzgpAQug4x8jCOKOgTTENsLGkt
Product

lonidamine-encapsulating PEGylated peptide nanoparticles

Hydrodynamic diameter: ~ 130 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

lonidamine-encapsulating PEGylated peptide nanoparticles

Hydrodynamic diameter: ~ 80 - ~ 300 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Product

lonidamine-encapsulating PEGylated peptide nanoparticles

Size: not specified

Medium: FBS solution

Support: none

Method 4

Type: Physical formation
Source:
Product

lonidamine-encapsulating PEGylated peptide nanoparticles

Size: not specified

Medium: FBS solution

Support: none

Method 5

Type: Physical formation
Source:
Product

lonidamine-encapsulating PEGylated peptide nanoparticles

Size: not specified

Medium: FBS solution

Support: none

References

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