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TD/ICG-loaded PEGylated mesoporous silica-coated CuS nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

copper(II) sulfide

copper selenide copper sulfide covellite Cu2-xS CuS CS
Type Single Compound
Formula CuS
Role core
2

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role layer
3

2-[methoxypoly(ethyleneoxy)9-12 propyl]trimethoxysilane moiety

mPEG-silane moiety
Type Polymer
Formula
Role layer
4

(3-aminopropyl)trimethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety 3-aminopropyltriethoxysilane moiety γ-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role layer
5

sodium 4-[2-[(1E,3E,5E,7Z)-7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-2-ylidene]hepta-1,3,5-trienyl]-1,1-dimethylbenzo[e]indol-3-ium-3-yl]butane-1-sulfonate

3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide Indocyanine Green indocyanine green IC-Green® IGG ICG IcG
Type Single Compound
Formula C43H47N2NaO6S2
Role loaded material
6

myristyl alcohol

1-tetradecanol tetradecanol
Type Single Compound
Formula C14H30O
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
fluorescence spectroscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
female nude mouse bearing breast cancer (4T1) tumors

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. sBNug4uX
Product

TD/ICG-loaded PEGylated mesoporous silica-coated CuS nanoparticles

Thickness: ~ 35 nm

Medium/Support: none

References

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