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doxorubicin-loaded 5,6-dimethylxanthenone-4-acetic acid-conjugated methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide) micelles

Based on

1 Articles
2017 Most recent source

Composition

1

5,6-dimethylxanthenone-4-acetic acid-conjugated methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide) nanoparticles

5,6-dimethylxanthenone-4-acetic acid-conjugated methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide) micelles methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide)-5,6-dimethylxanthenone-4-acetic acid micelles DMXAA-conjugated mPEG-b-PHEA micelles DMXAA-conjugated mPEG-b-PHEA NP mPEG-b-PHEA-DMXAA micelles
Type Nano Material
Formula
Role raw materials
2

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast carcinoma MCF-7 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. p8XQSDVZDMk2w
  2. JtFn9AoLSFnIrXmhXe117vWJe9b
Product

doxorubicin-loaded 5,6-dimethylxanthenone-4-acetic acid-conjugated methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide) micelles

Hydrodynamic radius: 22.1 - 40.9 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

doxorubicin-loaded 5,6-dimethylxanthenone-4-acetic acid-conjugated methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide) micelles

Hydrodynamic radius: ~ 22 - 30 nm

Medium: fetal bovine serum/phosphate buffer solution

Support: none

References

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