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5,6-dimethylxanthenone-4-acetic acid-conjugated methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide) nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

5,6-dimethylxanthenone-4-acetic acid-conjugated methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide)

methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide)-5,6-dimethylxanthenone-4-acetic acid DMXAA-conjugated mPEG-b-PHEA mPEG-b-PHEA-DMXAA
Type Polymer
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
5,6-dimethylxanthenone-4-acetic acid release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast carcinoma MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

5,6-dimethylxanthenone-4-acetic acid-conjugated methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide) nanoparticles

Hydrodynamic radius: ~ 19 - 24 nm

Medium: fetal bovine serum/phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • 5,6-dimethylxanthenone-4-acetic acid
  • methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide)
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Product

5,6-dimethylxanthenone-4-acetic acid-conjugated methoxy poly(ethylene glycol)-b-poly-((N-2-hydroxyethyl)-aspartamide) nanoparticles

Hydrodynamic radius: 15.3 - 22.1 nm

Medium/Support: none

References

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