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plasmid DNA-loaded 1,2-dioleoyl-3-trimethylammonium-propane/(3β-[N-(N',N'-dimethylaminoethane)-carbamoyl])-cholesterol/dioleoylphosphocholine/dioleoylphosphatidylethanolamine lipoplexes

Based on

1 Articles
2017 Most recent source

Composition

1

HEPES buffer

Type Complex Compound
Formula
Role core
2

1,2-dioleoyl-3-trimethylammonium-propane/(3β-[N-(N',N'-dimethylaminoethane)-carbamoyl])-cholesterol/dioleoylphosphocholine/dioleoylphosphatidylethanolamine

DOTAP/DC-Chol/DOPC/DOPE
Type Complex Compound
Formula
Role layer
3

plasmid deoxyribonucleic acid

pDNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
nanobiotechnology

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
Chinese hamster ovarian (CHO) cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

plasmid DNA-loaded 1,2-dioleoyl-3-trimethylammonium-propane/(3β-[N-(N',N'-dimethylaminoethane)-carbamoyl])-cholesterol/dioleoylphosphocholine/dioleoylphosphatidylethanolamine lipoplexes

Method 2

Type: Physical formation
Source:
Product

plasmid DNA-loaded 1,2-dioleoyl-3-trimethylammonium-propane/(3β-[N-(N',N'-dimethylaminoethane)-carbamoyl])-cholesterol/dioleoylphosphocholine/dioleoylphosphatidylethanolamine lipoplexes

References

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