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doxorubicin hydrochloride-loaded sericin-coated MCM-41 mesoporous silica nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

MCM-41 mesoporous silica nanoparticles

MSN
Type Nano Material
Formula
Role core
2

(3-aminopropyl)trimethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety γ-aminopropyltriethoxysilane moiety 3-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role layer
3

glutaraldehyde

Type Single Compound
Formula C5H8O2
Role layer
4

sericin

Type Biomolecule
Formula
Role layer
5

doxorubicin hydrogen chloride

adriblastin hydrochloride doxorubicin hydrochloride adriamycin hydrochloride doxorubicin hydrochoride adriblastin HCl salt adriamycin HCl salt DOX hydrochloride DXR hydrochloride doxorubicin HCl DOX*HCl DOX-HCl DOX·HCl DXR HCl DXR*HCl Dox HCl Dox*HCl DOXS
Type Single Compound
Formula C27H29NO11*HCl
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female BALB/c nude mouse bearing human breast cancer MCF-7/ADR xenograft

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. 8irzmXNuaV1Y
  2. Cs0R5E
  3. XkvZj3XJ
Product

doxorubicin hydrochloride-loaded sericin-coated MCM-41 mesoporous silica nanoparticles

Diameter: ~ 100 - ~ 280 nm

Medium/Support: none

References

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