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SFN nanocrystals

Based on

2 Articles
2017 Most recent source

Composition

1

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
breast cancer MDA-MB-231 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  1. fDnwJfUHcPPDOdxVeW
  2. dTCcxOdsAH1UkkT15dhgg2K1VDssScrY8MbirbzDiUGvYiXtj2VounPutTes
Product

SFN nanocrystals

Hydrodynamic diameter: ~ 250 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  1. SoLWBRljZIiOZl9w48
  2. K9ReHcGQ6h4SdgiwdClcOMwi7EdZzDJyCSHmzqxaKzLvIhggA5ayj5sZjn86
Product

SFN nanocrystals

Hydrodynamic diameter: ~ 68 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  1. 2POMIK721DklTZLPK3
  2. noQED7mANPL6UqO64xRK8tk6vETMghKD9mYSujHLfAnrABjZDAVOOPxtbchT
Product

SFN nanocrystals

Hydrodynamic diameter: ~ 110 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  1. t0Hj8m1C3w4zQNZRY8
  2. gBgwNZLC8a5f9vM5IlLEe0g2q9tmBDCElU4FOvCtFlkGTjNBbjyZlGLXlpCc
Product

SFN nanocrystals

Hydrodynamic diameter: ~ 886 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  1. ZicLuLA
  2. BtxVP
Product

SFN nanocrystals

Size: not specified

Medium/Support: none

References

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