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docetaxel-loaded PEGylated liposomes

Based on

1 Articles
2017 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

POPC/DSPE-PEG2000

Type Complex Compound
Formula
Role layer
3

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
BxPC3 human pancreatic cancer tumor-bearing Balb/c nude mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • DSPE-PEG2000
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Product

docetaxel-loaded PEGylated liposomes

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

docetaxel-loaded PEGylated liposomes

Size: not specified

Medium: phosphate buffer solution

Support: none

References

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