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pDNA-loaded HC-functionalized TMCSH nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

thiolated trimethyl chitosan

thiolated TMC TMCSH
Type Biomolecule
Formula
Role core
2

brain derived neurotrophic factor-encoding plasmid DNA

BDNF encoding pDNA
Type Biomolecule
Formula
Role loaded material
3

HC-PEG fragment

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse with sciatic nerve crush injury

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

pDNA-loaded HC-functionalized TMCSH nanoparticles

Hydrodynamic diameter: 261.2 - 264.4 nm

Medium: HEPES buffered saline

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. eN4eOR5R8kK31N60x
Product

pDNA-loaded HC-functionalized TMCSH nanoparticles

Size: not specified

Medium/Support: none

References

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