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dexamethasone/RNA-loaded polycaprolactone-polyethylenimine/polycaprolactone-polyethyleneglycol hybrid micelles

Based on

1 Articles
2017 Most recent source

Composition

1

polycaprolactone-polyethylenimine/polycaprolactone-polyethyleneglycol mixture

PCL-PEI/PCL-PEG mixture
Type Complex Compound
Formula
Role carriers
2

(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

dexamethasone Dex DEX DXM
Type Single Compound
Formula C22H29FO5
Role loaded material
3

P65 siRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
bone marrow-derived macrophages

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • polycaprolactone-poly(ethylene glycol)
  • polycaprolactone-polyethyleneimine
  • (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  1. Qx8fxF84WjGtyGyqwwgomWL66t
Product

dexamethasone/RNA-loaded polycaprolactone-polyethylenimine/polycaprolactone-polyethyleneglycol hybrid micelles

Hydrodynamic diameter: 95.0 - 103.4 nm

Medium/Support: none

References

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