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poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)-coated siLuc-loaded 4-mercapto-N-(2-(piperidin-1-yl)ethyl)butanamide/1-hexanethiol-modified polyester nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

1

siLuc-loaded 4-mercapto-N-(2-(piperidin-1-yl)ethyl)butanamide/1-hexanethiol-modified polyester nanoparticles

siLuc-loaded amino thiol/alkyl thiol-modified polyester NP
Type Nano Material
Formula
Role core
2

poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

PEO101-PPO56-PEO101 Pluronic® F-68
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
A549 human non-small cell lung cancer (NSCLC) cells with expressing luciferase (A549-Luc)

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • octanedioic acid dichloride
  • trimethylolpropane allyl ether
  1. MoWsiTnxNrbY20H
  2. 8DajTDatA5eGHm5SILLI
Product

poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)-coated siLuc-loaded 4-mercapto-N-(2-(piperidin-1-yl)ethyl)butanamide/1-hexanethiol-modified polyester nanoparticles

Size: ~ 123 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • octanedioic acid dichloride
  • trimethylolpropane allyl ether
  1. YoeVRGaJ66d5eeE
  2. N8wOxDqHZTOnQQFCqpOF
Product

poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)-coated siLuc-loaded 4-mercapto-N-(2-(piperidin-1-yl)ethyl)butanamide/1-hexanethiol-modified polyester nanoparticles

Size: not specified

Medium/Support: none

References

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