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HIV-Gag FK10-specific CTL conjugated with IL-15Sa-loaded nanocapsules

Based on

1 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

CTL clone specific for HIV Gag-FLGKIWPSYK epitope

HIV-Gag FK10-specific cytotoxic T-lymphocytes HIV-Gag FK10-specific CTL
Type Bioobject
Formula
Role core
2

IL15Sa-loaded interbilayer-crosslinked multilamellar vesicles

IL15Sa-loaded ICMV nanocapsules IL15Sa-loaded ICMV IL15-loaded NC
Type Nano Material
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
immunodeficient NOD-scid IL2Rγ<sup>-/-</sup> (NSG) mouse reconstituted with CD4<sup>+</sup> T-cells from HLA-A02<sup>+</sup> HIV-negative donor and infected with CXCR4-tropic HIV molecular clone LAI

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. uylPF42jt5Wy4D36jyMR79Oo222Li45drAoo4y
  2. WGc4j
Product

HIV-Gag FK10-specific CTL conjugated with IL-15Sa-loaded nanocapsules

Size: not specified

Medium/Support: none

References

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