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trastuzumab-conjugated gold nanoparticles colloid

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

amphiphilic polymer-wrapped Au nanoparticles

polymer-coated Au NP
Type Nano Material
Formula
Role raw materials
2

NH2-PEG-NH2

Type Polymer
Formula
Role graft
3

AlexaFluor 660-labeled trastuzumab

AF660-labeled Tz
Type Biomolecule
Formula
Role graft

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Balb/c nude mouse bearing MCF-7 xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Product

trastuzumab-conjugated gold nanoparticles colloid

Hydrodynamic diameter: 13.6 - 23.0 nm

Medium: serum

Support: none

Method 2

Type: Physical formation
Source:
Product

trastuzumab-conjugated gold nanoparticles colloid

Hydrodynamic diameter: 7.0 - 18.8 nm

Medium: serum

Support: none

Method 3

Type: Physical formation
Source:
Product

trastuzumab-conjugated gold nanoparticles colloid

Hydrodynamic diameter: 17.5 - 18.7 nm

Medium: water

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • AlexaFluor 660-labeled trastuzumab
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Product

trastuzumab-conjugated gold nanoparticles colloid

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Product

trastuzumab-conjugated gold nanoparticles colloid

Hydrodynamic diameter: 10.9 - 11.7 nm

Medium: water

Support: none

References

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