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doxorubicin-loaded 2-cyano-6-amidobenzothiazole-modified gold nanoparticles colloid

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

gold

Type Single Compound
Formula Au
Role core
2

2-cyano-6-amidobenzothiazole-terminated polyethylene glycol thiol

SH-PEG-CABT
Type Polymer
Formula
Role layer
3

thiol-alkyl-hydrazone-modified doxorubicin

thiol-alkyl-hydrazone-modified DOX thiol-hydrazone doxorubicin thiol-modified doxorubicin SH-Hyz-DOX DOX-SH
Type Single Compound
Formula C30H35N3O11S
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
murine glioma C6 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

doxorubicin-loaded 2-cyano-6-amidobenzothiazole-modified gold nanoparticles colloid

Hydrodynamic diameter: ~ 45 nm

Medium: Dulbecco's modified Eagle medium

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

doxorubicin-loaded 2-cyano-6-amidobenzothiazole-modified gold nanoparticles colloid

Hydrodynamic diameter: ~ 45 nm

Medium: Dulbecco's modified Eagle medium with fetal calf serum

Support: none

References

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