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PTX-loaded Ep23 aptamer/K237 peptide-modified MPEG-PLA/HOOC-PEG-PLA nanoparticles

Based on

1 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

MPEG-PLA/HOOC-PEG-PLA complex

Type Complex Compound
Formula
Role core
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
3

5'-amino modified EpCAM RNA aptamer

Type Biomolecule
Formula
Role layer
4

K237 peptide

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
4T1 breast tumor-bearing female BALB/c nude mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. d2Y34LuyGkA4fJaJUOvJDbTBp21fSDY219qHy0ph94PxyTw86cBEOBN9hYrnxgjq03edQZVoNWu4ALSsqtpwawkWQxpUDGx5KT9gRX6
  2. newdpMpA7013yy00
Product

PTX-loaded Ep23 aptamer/K237 peptide-modified MPEG-PLA/HOOC-PEG-PLA nanoparticles

Size: not specified

Medium/Support: none

References

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