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firefly luciferase-encoding mRNA loaded poly(β-amino esters) nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

poly (1,11-diamino-3,6,9-trioxaundecane/1,11-diamino-3,6,9-trioxaundecane/4-(2-aminomethyl)morpholine/4-(2-aminomethyl)morpholine/1-aminododecane/1-aminododecane/C27H32O8/C27H32O8)

Type Polymer
Formula
Role carriers
2

firefly luciferase-encoding mRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability in serum

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57BL/6 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • firefly luciferase-encoding mRNA
  • sodium acetate buffer
Product

firefly luciferase-encoding mRNA loaded poly(β-amino esters) nanoparticles

Size: not specified

Medium: sodium acetate buffer

Support: none

Method 2

Type: Physical formation
Source:
Product

firefly luciferase-encoding mRNA loaded poly(β-amino esters) nanoparticles

Hydrodynamic diameter: 189.4 - 586.6 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
Product

firefly luciferase-encoding mRNA loaded poly(β-amino esters) nanoparticles

Size: not specified

Medium: sodium acetate aqueous solution

Support: none

Method 4

Type: Physical formation
Source:
Product

firefly luciferase-encoding mRNA loaded poly(β-amino esters) nanoparticles

Hydrodynamic diameter: 211.1 - 578.7 nm

Medium: phosphate buffer solution

Support: none

Method 5

Type: Physical formation
Source:
Product

firefly luciferase-encoding mRNA loaded poly(β-amino esters) nanoparticles

Size: not specified

Medium: sodium acetate aqueous solution

Support: none

References

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