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tPA/alendronate-functionalized platelet membrane-coated m-dextran nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

m-dextran

Type Biomolecule
Formula
Role core
2

biotinylated platelet membrane

Type Complex Compound
Formula
Role layer
3

streptavidin

Type Biomolecule
Formula
Role layer
4

biotinylated tissue plasminogen activator

biotinylated tPA
Type Complex Compound
Formula
Role layer
5

4-(N-maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt

4-(N-maleimidomethyl)cyclohexane-1-carboxylate-3-sulfo-N-hydroxysuccinimide ester sodium salt sulfosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate sodium salt sulfosuccinimidyl 4-[N-maleimidomethyl] cyclohexane-1-carboxylate sulfosuccinimidyl-4-(N-maleimidomethyl) cyclohexane-1-carboxylate sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate sulfosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate sulphosuccinimidyl 4-N-maleimidomethyl cyclohexane-1-carboxylate 4-(N-maleimidomethyl)cyclohexane-1-carboxylate sodium salt Sulfo-SMCC sulfo-SMCC
Type Single Compound
Formula C16H17N2NaO9S
Role layer
6

(1-hydroxy-4-aminobutylidene)-1,1-bisphosphonic acid

alendronic acid Alendronate alendronate Ald AD
Type Single Compound
Formula C4H13NO7P2
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
lung of fibrinogen/thromboplastin-treated Nod/SCID mouse

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Preparation

Method 1

Type: Physical formation
Source:
Product

tPA/alendronate-functionalized platelet membrane-coated m-dextran nanoparticles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Product

tPA/alendronate-functionalized platelet membrane-coated m-dextran nanoparticles

Size: not specified

Medium: FBS solution

Support: none

References

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