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PTX-S-S-OA/TPGS NP

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

2'-O-((2-oxo-2-(2-((Z)-oleoyloxy)ethoxy)ethyldithio)acetyl)taxol

PTX-SS-OA
Type Single Compound
Formula C71H91NO19S2
Role core
2

tocopheryl polyethylene glycol succinate

TPGS2k
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female nude mouse bearing human epidermoid carcinoma (KB-3-1) xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 2'-O-((2-oxo-2-(2-((Z)-oleoyloxy)ethoxy)ethyldithio)acetyl)taxol
  • tocopheryl polyethylene glycol succinate
  1. rl5vDpw9zU9hOhdu
Product

PTX-S-S-OA/TPGS NP

Diameter: ~ 110 nm

Hydrodynamic diameter: 107.2 - 112.2 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

PTX-S-S-OA/TPGS NP

Diameter: ~ 110 nm

Hydrodynamic diameter: ~ 120 nm

Medium: phosphate buffer solution/fetal bovine serum

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
Product

PTX-S-S-OA/TPGS NP

Diameter: ~ 110 nm

Hydrodynamic diameter: ~ 120 nm

Medium: phosphate buffer solution/fetal bovine serum

Support: none

References

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