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cancer-cell-membrane-coated paclitaxel-loaded polymeric nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

polycaprolactone

PCL
Type Polymer
Formula
Role core
2

poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

Pluronic F68 F68
Type Polymer
Formula
Role layer
3

Paclitaxel

Plaxicel Abraxane Paxene Taxol PCL PAC PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
4

4T1 cell membrane

Type Bioobject
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
4T1 mammary breast cancer cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

cancer-cell-membrane-coated paclitaxel-loaded polymeric nanoparticles

Hydrodynamic diameter: 174.8 - 176.0 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Product

cancer-cell-membrane-coated paclitaxel-loaded polymeric nanoparticles

Size: not specified

Medium: FBS solution

Support: none

Method 3

Type: Physical formation
Source:
Product

cancer-cell-membrane-coated paclitaxel-loaded polymeric nanoparticles

Size: not specified

Medium: FBS solution

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
Product

cancer-cell-membrane-coated paclitaxel-loaded polymeric nanoparticles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • 4T1 mammary breast cancer cells
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Product

cancer-cell-membrane-coated paclitaxel-loaded polymeric nanoparticles

Size: not specified

Medium/Support: none

References

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