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firefly luciferase-encoding mRNA loaded PEGylated poly(β-amino esters) nanoparticles

Based on

1 Articles
2016 Most recent source

Composition

1

mixture of substance based on (poly (1,11-diamino-3,6,9-trioxaundecane/1,11-diamino-3,6,9-trioxaundecane/3-amino-1,2-propanediol/3-amino-1,2-propanediol/1-aminododecane/1-aminododecane/C27H32O8/C27H32O8)/n = 45)

Type Complex Compound
Formula
Role carriers
2

firefly luciferase-encoding mRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
stability in serum

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Applications

Characterization

Biological effects

Biological system Test details Source
C57BL/6 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • n = 45
  • poly (1,11-diamino-3,6,9-trioxaundecane/1,11-diamino-3,6,9-trioxaundecane/3-amino-1,2-propanediol/3-amino-1,2-propanediol/1-aminododecane/1-aminododecane/C27H32O8/C27H32O8)
  1. i0TIN1F
Product

firefly luciferase-encoding mRNA loaded PEGylated poly(β-amino esters) nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • n = 45
  • poly (1,11-diamino-3,6,9-trioxaundecane/1,11-diamino-3,6,9-trioxaundecane/3-amino-1,2-propanediol/3-amino-1,2-propanediol/1-aminododecane/1-aminododecane/C27H32O8/C27H32O8)
  1. JngIspo
Product

firefly luciferase-encoding mRNA loaded PEGylated poly(β-amino esters) nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • n = 45
  • poly (1,11-diamino-3,6,9-trioxaundecane/1,11-diamino-3,6,9-trioxaundecane/3-amino-1,2-propanediol/3-amino-1,2-propanediol/1-aminododecane/1-aminododecane/C27H32O8/C27H32O8)
  1. wAXO29S
Product

firefly luciferase-encoding mRNA loaded PEGylated poly(β-amino esters) nanoparticles

Method 4

Type: Physical formation
Source:
Starting materials
  • n = 45
  • poly (1,11-diamino-3,6,9-trioxaundecane/1,11-diamino-3,6,9-trioxaundecane/3-amino-1,2-propanediol/3-amino-1,2-propanediol/1-aminododecane/1-aminododecane/C27H32O8/C27H32O8)
  1. 5uYDDVn
Product

firefly luciferase-encoding mRNA loaded PEGylated poly(β-amino esters) nanoparticles

Method 5

Type: Physical formation
Source:
Starting materials
  • n = 45
  • poly (1,11-diamino-3,6,9-trioxaundecane/1,11-diamino-3,6,9-trioxaundecane/3-amino-1,2-propanediol/3-amino-1,2-propanediol/1-aminododecane/1-aminododecane/C27H32O8/C27H32O8)
  1. F3nedFD
Product

firefly luciferase-encoding mRNA loaded PEGylated poly(β-amino esters) nanoparticles

References

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