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DY-633-encapsulated ssDNA-conjugated PMOXA7-PDMS42-PMOXA7/PDMS75-PMOXA37-PEG3-N3 polymersomes

Based on

1 Articles
2016 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

DY-633

Type Complex Compound
Formula
Role loaded material
3

poly(2-methyloxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyloxazoline) triblock copolymer

PMOXA7-PDMS42-PMOXA7 triblock copolymer PMOXA7-PDMS42-PMOXA7
Type Polymer
Formula
Role layer
4

poly(dimethylsiloxane)-block-poly(2-methyloxazoline) diblock copolymer

PDMS75-PMOXA37-PEG3-N3 diblock copolymer PDMS75-PMOXA37-PEG3-N3
Type Polymer
Formula
Role graft
5

dibenzocyclooctyl-terminated single-stranded deoxyribonucleic acid

dibenzocyclooctyl-terminated ssDNA DBCO-terminated ssDNA
Type Biomolecule
Formula
Role layer

Properties

Applications

Characterization

Biological effects

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • poly(dimethylsiloxane)-block-poly(2-methyloxazoline) diblock copolymer
  • poly(2-methyloxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyloxazoline) triblock copolymer
  1. q5s21OFKM3ir2Ws3bQ
Product

DY-633-encapsulated ssDNA-conjugated PMOXA7-PDMS42-PMOXA7/PDMS75-PMOXA37-PEG3-N3 polymersomes

Diameter: ~ 110 nm

Thickness: ~ 12 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • poly(dimethylsiloxane)-block-poly(2-methyloxazoline) diblock copolymer
  • poly(2-methyloxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyloxazoline) triblock copolymer
  1. lPAZIQ9cVq4Kd8gZLM
Product

DY-633-encapsulated ssDNA-conjugated PMOXA7-PDMS42-PMOXA7/PDMS75-PMOXA37-PEG3-N3 polymersomes

Diameter: ~ 180 nm

Thickness: ~ 12 nm

Medium: phosphate buffer solution

Support: none

References

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