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anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PCB-P(DPAx-co-DMAEMAy)-PG nanomicelles

GDDC4 nanomicelles GDDC4-M GDDC-M
Type Nano Material
Formula
Role carriers
2

anti-PLK-1 small interfering RNA

anti-PLK-1 siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
293A cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • anti-PLK-1 small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. x9Dzb7VTKl79I6X7M5M0ZlyG9jTHei5li8c52CI
Product

anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • anti-PLK-1 small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. 2cVmqar3AgWU0N10wNqp89hYotSV06X8TtE8sdP
Product

anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • anti-PLK-1 small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. sGK4VgfV8WODmhcSSAYeSTdzw9J7ZjUtCU3AhoK
Product

anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • anti-PLK-1 small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. id8OWoXU8GG2OxPlPBKqqlbxsM2boeGrsderS5P
Product

anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • anti-PLK-1 small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. s5DSnGWuzFocAXmurXg6eAuiRiFEHAHHkMg6MnB
Product

anti-PLK-1 siRNA-loaded GDDC4 nanomicelles

Size: not specified

Medium: phosphate buffer solution

Support: none

References

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