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GDDC-M/anti-Luc siRNA complexes

Based on

1 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PCB-P(DPAx-co-DMAEMAy)-PG nanomicelles

GDDC8 nanomicelles GDDC8-M GDDC-M
Type Nano Material
Formula
Role carriers
2

Cy5-labeled small interfering RNA

Cy5-labeled siRNA Cy5-siRNA
Type Biomolecule
Formula
Role loaded material

Properties

Applications

Area Application Source
genetic engineering

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Characterization

Biological effects

Biological system Test details Source
female C57BL/6 mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • small interfering ribonucleic acid
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. 7U0YMvRWzbEAlPTFAwEXdUhALvEfXx8g1oAPjFg
Product

GDDC-M/anti-Luc siRNA complexes

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • anti-luciferase small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. usSPCF1N4XwhTvMqbDXowNGkkoJrxfR3NBA2E1C
Product

GDDC-M/anti-Luc siRNA complexes

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • anti-luciferase small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. P5IMCB7nF8rUjWeYumkHU7P57EX45zdnGUrylJO
Product

GDDC-M/anti-Luc siRNA complexes

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • Cy5-labeled small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. yhQLZgdhO8UlsBRzY2FVimVE8iS4eFKzlkCtRz4
Product

GDDC-M/anti-Luc siRNA complexes

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • anti-luciferase small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. vN1tMtK1uvJoICl7pSaE37Cxyzj3z0mebnRdgdh
Product

GDDC-M/anti-Luc siRNA complexes

References

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