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GDDC-M/anti-Luc siRNA complexes

Based on

11 Articles
2017 Most recent source

Composition

1

PEG-g-PEI-SPION

Type Nano Material
Formula
Role carriers
2

Bcl-2 small interfering ribonucleic acid

Bcl-2 siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
genetic engineering

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medicine/veterinary

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
athymic male BALB/c nude mouse bearing human colonic carcinoma HCT-8/T tumor xenograft

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • small interfering ribonucleic acid
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. kiwAtsuQUhOxqrE2Z96pmgE4CsjlXD7q2id3fir
Product

GDDC-M/anti-Luc siRNA complexes

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • polymer
  • tetradecane-polyethylene glycol
  • small interfering RNA
  1. HI3y4JZM6bzFXCEXV6R
Product

GDDC-M/anti-Luc siRNA complexes

Hydrodynamic diameter: ~ 25 - ~ 120 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • anti-luciferase small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. R8KAnDTUDsHK7sdfVLfXVPk8qrp4l7iqdZMlFUF
Product

GDDC-M/anti-Luc siRNA complexes

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  1. lj1GVuSX40B2BJi1
  2. V8wKa2
Product

GDDC-M/anti-Luc siRNA complexes

Hydrodynamic diameter: ~ 12 nm

Medium: water

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • Cy5-labeled small interfering RNA
  • poly(carboxybetaine)-poly(dimethylaminoethyl methacrylate-co-diisopropylethyl methacrylate)-guanidinated poly(aminoethyl methacrylate) triblock polycation
  1. 8oiu03mGfMrxodjkiUiQb2drxKCEPSYu3EiS6KN
Product

GDDC-M/anti-Luc siRNA complexes

Size: not specified

Medium: phosphate buffer solution

Support: none

References

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